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SMAD4 Antikörper (AA 255-284)

Name: SMAD4 Antikörper (AA 255-284)
SKU: ABIN392165
Price: 445.5 EUR
Availability: InStock

SMAD4 Reaktivität: Human, Maus WB, IF Wirt: Kaninchen Polyclonal RB14714 unconjugated

Western blot analysis of SD4 Antibody (arrow) using rabbit polyclonal SD4 Antibody (ABIN392165 and ABIN2841882). (SMAD4 Antikörper (AA 255-284))

All lanes : Anti-SD4 Antibody at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: Neuro-2a whole cell lysate Lane 4: NIH/3T3 whole cell lysate Lysates/proteins at 20 μg per lane. (SMAD4 Antikörper (AA 255-284))

Anti-SD4 Antibody at 1:2000 dilution + Neuro-2a whole cell lysate Lysates/proteins at 20 μg per lane. (SMAD4 Antikörper (AA 255-284))

Confocal immunofluorescent analysis of SD4 Antibody (ABIN392165 and ABIN2841882) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (SMAD4 Antikörper (AA 255-284))

4 Abbildungen

(1 reference)

Produktnummer ABIN392165

Datenblatt (PDF)

Target Alle SMAD4 Antikörper anzeigen

SMAD4 (SMAD Family Member 4 (SMAD4))
Bindungsspezifität
12

11

10

7

7

7

6

5

4

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1
AA 255-284
Reaktivität
95

39

36

4

3

3

2

2

2

2

2

2

1

1
Human, Maus
Wirt
84

11

1
Kaninchen
Passende Sekundärantikörper
Klonalität
72

24
Polyklonal
Konjugat
52

9

8

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1
Dieser SMAD4 Antikörper ist unkonjugiert
Applikation
64

45

38

27

22

8

8

7

6

3

2

2

2

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF)

Homologie

Rat

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This SMAD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-284 amino acids from human SMAD4.

Klon

RB14714

Isotyp

Ig Fraction

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SMAD4 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

IF: 1:10~50. WB: 1:1000. WB: 1:2000. WB: 1:1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Lessard, Rivas, Alves-Wagner, Hirshman, Gallagher, Constantin-Teodosiu, Atkins, Greenhaff, Qi, Gustafsson, Fielding, Timmons, Britton, Koch, Goodyear: "Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks." in: Diabetes, Vol. 62, Issue 8, pp. 2717-27, (2013) (PubMed).
Target

SMAD4 (SMAD Family Member 4 (SMAD4))

Andere Bezeichnung

SMAD4 (SMAD4 Produkte)

Synonyme

smad4 antikoerper, DPC4 antikoerper, JIP antikoerper, MADH4 antikoerper, MYHRS antikoerper, AW743858 antikoerper, D18Wsu70e antikoerper, Madh4 antikoerper, XSmad4alpha antikoerper, Xsmad4 antikoerper, dpc4 antikoerper, jip antikoerper, madh4 antikoerper, xsmad4a antikoerper, SMAD family member 4 antikoerper, Smad4 protein antikoerper, SMAD family member 4, gene 1 L homeolog antikoerper, SMAD4 antikoerper, smad4 antikoerper, Smad4 antikoerper, smad4.1.L antikoerper

Hintergrund

SMAD4 is the common SMAD (co-SMAD)mediator of signal transduction by TGF-beta (transforming growth factor). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.

Molekulargewicht

60439

Gen-ID

4089

NCBI Accession

NP_005350

UniProt

Q13485

Pathways

Zellzyklus, Chromatin Binding, Autophagie