alpha Actinin 4 Antikörper (N-Term)
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- Target Alle alpha Actinin 4 (ACTN4) Antikörper anzeigen
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
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Bindungsspezifität
- AA 192-220, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser alpha Actinin 4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Homologie
- B, C, M, Rat
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This ACTN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-220 amino acids from the N-terminal region of human ACTN4.
- Klon
- RB15650
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product ACTN4 Primärantikörper
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anti-Actinin, alpha 4 (ACTN4) (AA 592-701) antibody
ACTN4 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 4D10 unconjugated
anti-Actinin, alpha 4 (ACTN4) (AA 1-269) antibodyACTN4 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) (C-Term) antibodyACTN4 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) antibodyACTN4 Reaktivität: Human WB, IP, IF Wirt: Kaninchen Monoclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) (AA 160-440) antibodyACTN4 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) (AA 785-813), (C-Term) antibodyACTN4 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB15705 unconjugated
anti-Actinin, alpha 4 (ACTN4) (N-Term) antibodyACTN4 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio), Pferd, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) antibodyACTN4 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) (AA 1-911) antibodyACTN4 Reaktivität: Human WB, IF, PLA Wirt: Kaninchen Polyclonal unconjugated
anti-Actinin, alpha 4 (ACTN4) (AA 561-661) antibodyACTN4 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
- Andere Bezeichnung
- ACTN4 (ACTN4 Produkte)
- Hintergrund
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This protein is a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and is thought to be involved in metastatic processes. Mutations in the gene encoding this protein have been associated with focal and segmental glomerulosclerosis.
- Molekulargewicht
- 104854
- Gen-ID
- 81
- NCBI Accession
- NP_004915
- UniProt
- O43707
- Pathways
- Proton Transport
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