Transglutaminase 2 Antikörper (AA 429-458)

Produktnummer ABIN392285

Produktdetails anti-Transglutaminase 2 Antikörper

Target: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Bindungsspezifität: AA 429-458

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Transglutaminase 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Transglutaminase (TGM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 429-458 amino acids from the Central region of human Transglutaminase (TGM2).

Klon: RB13081

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Transglutaminase 2

Target: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Andere Bezeichnung: Transglutaminase (TGM2) (TGM2 Produkte)

Synonyme: G-ALPHA-h antikoerper, GNAH antikoerper, TG2 antikoerper, TGC antikoerper, tgm2 antikoerper, zgc:101081 antikoerper, TgaseII antikoerper, TGM2 antikoerper, fc12b04 antikoerper, wu:fc12b04 antikoerper, zgc:136700 antikoerper, TGL2 antikoerper, G[a]h antikoerper, TGase2 antikoerper, tTG antikoerper, tTGas antikoerper, transglutaminase 2 antikoerper, transglutaminase 2, C polypeptide A antikoerper, transglutaminase 2b antikoerper, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) antikoerper, transglutaminase 2, C polypeptide antikoerper, TGM2 antikoerper, tgm2a antikoerper, Tgm2 antikoerper, tgm2b antikoerper

Hintergrund: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It has been identified as the autoantigen implicated in celiac disease.

Molekulargewicht: 77329

Gen-ID: 7052

NCBI Accession: NP_004604, NP_945189

UniProt: P21980

Pathways: Tube Formation, Thromboxane A2 Receptor Signaling