Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This CYP2R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 464-496 amino acids from the C-terminal region of human CYP2R1.
cytochrome P450 family 2 subfamily R member 1 antikoerper, cytochrome P450, family 2, subfamily R, polypeptide 1 antikoerper, cytochrome P450, family 2, subfamily r, polypeptide 1 antikoerper, CYP2R1 antikoerper, cyp2r1 antikoerper, Cyp2r1 antikoerper
Hintergrund
CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in CYP2R1 gene has been associated with selective 25-hydroxyvitamin D deficiency.