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MAP3K6 Antikörper (C-Term)

MAP3K6 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB0946 unconjugated
Produktnummer ABIN392411
  • Target Alle MAP3K6 Antikörper anzeigen
    MAP3K6 (Mitogen-Activated Protein Kinase Kinase Kinase 6 (MAP3K6))
    Bindungsspezifität
    • 8
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1028-1058, C-Term
    Reaktivität
    • 38
    • 26
    • 3
    Human, Maus
    Wirt
    • 38
    • 2
    • 1
    Kaninchen
    Klonalität
    • 40
    • 1
    Polyklonal
    Konjugat
    • 15
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAP3K6 Antikörper ist unkonjugiert
    Applikation
    • 28
    • 26
    • 26
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This MEKK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1028-1058 amino acids from the C-terminal region of human MEKK6.
    Klon
    RB0946
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Han, Oh, Kang, Kim, Seo, Kim, Park, Kim: "Protein profiling in human sera for identification of potential lung cancer biomarkers using antibody microarray." in: Proteomics, Vol. 9, Issue 24, pp. 5544-52, (2009) (PubMed).

  • Target
    MAP3K6 (Mitogen-Activated Protein Kinase Kinase Kinase 6 (MAP3K6))
    Andere Bezeichnung
    MEKK6 (MAP3K6 Produkte)
    Synonyme
    ASK2 antikoerper, MAPKKK6 antikoerper, MEKK6 antikoerper, Ask2 antikoerper, mitogen-activated protein kinase kinase kinase 6 antikoerper, MAP3K6 antikoerper, Map3k6 antikoerper
    Hintergrund
    Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK6 activates the JNK, but not ERK or p38 kinase pathways.
    Molekulargewicht
    142596
    Gen-ID
    9064
    NCBI Accession
    NP_004663
    UniProt
    O95382
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