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MAP2K4 Antikörper (AA 235-264)

MAP2K4 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB11276 unconjugated
Produktnummer ABIN392418
  • Target Alle MAP2K4 Antikörper anzeigen
    MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
    Bindungsspezifität
    • 35
    • 21
    • 10
    • 10
    • 9
    • 9
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 235-264
    Reaktivität
    • 145
    • 68
    • 49
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 138
    • 12
    Kaninchen
    Klonalität
    • 140
    • 11
    Polyklonal
    Konjugat
    • 80
    • 12
    • 9
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAP2K4 Antikörper ist unkonjugiert
    Applikation
    • 80
    • 62
    • 54
    • 20
    • 20
    • 15
    • 15
    • 13
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Zf, X, M
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This MEK4(MAP2K4) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-264 amino acids from human MEK4(MAP2K4).
    Klon
    RB11276
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product MAP2K4 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
    Andere Bezeichnung
    MEK4 (MAP2K4) (MAP2K4 Produkte)
    Hintergrund
    MAP2K4 is a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. MAP2K4 is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.
    Molekulargewicht
    44288
    Gen-ID
    6416
    NCBI Accession
    NP_001268364, NP_003001
    UniProt
    P45985
    Pathways
    MAPK Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
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