PAK2 Antikörper (N-Term)

Produktnummer ABIN392433

Produktdetails anti-PAK2 Antikörper

Target: PAK2 (P21-Activated Kinase 2 (PAK2))

Bindungsspezifität: AA 192-222, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-222 amino acids from the N-terminal region of human PAK2.

Klon: RB1221-1222

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PAK2

Target: PAK2 (P21-Activated Kinase 2 (PAK2))

Andere Bezeichnung: PAK2 (PAK2 Produkte)

Synonyme: PAK65 antikoerper, PAKgamma antikoerper, gamma-PAK antikoerper, 5330420P17Rik antikoerper, A130002K10Rik antikoerper, AI836325 antikoerper, D16Ertd269e antikoerper, PAK-2 antikoerper, mKIAA4182 antikoerper, pak2 antikoerper, cb422 antikoerper, kinase antikoerper, zgc:91798 antikoerper, wu:fb71h01 antikoerper, si:dz198m22.1 antikoerper, pak65 antikoerper, pakgamma antikoerper, PAKI antikoerper, Pak3 antikoerper, CH73-159L23.1 antikoerper, wu:fc52b03 antikoerper, zgc:113857 antikoerper, p21 (RAC1) activated kinase 2 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 2 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 2a antikoerper, p21 protein (Cdc42/Rac)-activated kinase 2 S homeolog antikoerper, p21 protein (Cdc42/Rac)-activated kinase 2b antikoerper, PAK2 antikoerper, Pak2 antikoerper, pak2a antikoerper, pak2.S antikoerper, pak2b antikoerper

Hintergrund: PAK2, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. It phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. PAK2 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. Expression is ubiquitous, with higher levels seen in skeletal muscle, ovary, thymus and spleen. PAK2 is autophosphorylated when activated by CDC42/p21. The protein structure contains 1 CRIB domain.

Molekulargewicht: 58043

Gen-ID: 5062

NCBI Accession: NP_002568

UniProt: Q13177

Pathways: MAPK Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Regulation of Lipid Metabolism by PPARalpha