PFKFB1 Antikörper (AA 259-289)

Produktnummer ABIN392772

Produktdetails anti-PFKFB1 Antikörper

Target: PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))

Bindungsspezifität: AA 259-289

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PFKFB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PFKFB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-289 amino acids from the Central region of human PFKFB1.

Klon: RB4038

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.

Haltbarkeit: 6 months

Details zu PFKFB1

Target: PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))

Andere Bezeichnung: PFKFB1 (PFKFB1 Produkte)

Synonyme: zgc:55328 antikoerper, wu:fi11h10 antikoerper, PFKFB1 antikoerper, F6PK antikoerper, HL2K antikoerper, PFRX antikoerper, Pfkfb01 antikoerper, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 antikoerper, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 S homeolog antikoerper, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 antikoerper, pfkfb1 antikoerper, PFKFB1 antikoerper, pfkfb1.S antikoerper, LOC100475853 antikoerper, Pfkfb1 antikoerper

Hintergrund: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).

Molekulargewicht: 54681

NCBI Accession: NP_001258733, NP_002616

UniProt: P16118

Pathways: Regulation of Carbohydrate Metabolic Process