Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This PPP3CC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 482-512 amino acids from the C-terminal region of human PPP3CC.
CALNA3 antikoerper, CNA3 antikoerper, PP2Bgamma antikoerper, Calnc antikoerper, ppp3cc antikoerper, sb:cb767 antikoerper, si:dkey-21k4.5 antikoerper, calna3 antikoerper, cna3 antikoerper, pp2bgamma antikoerper, im:7163784 antikoerper, zgc:158685 antikoerper, protein phosphatase 3 catalytic subunit gamma antikoerper, protein phosphatase 3, catalytic subunit, gamma isoform antikoerper, protein phosphatase 3, catalytic subunit, gamma isozyme, a antikoerper, protein phosphatase 3, catalytic subunit, gamma isozyme antikoerper, protein phosphatase 3, catalytic subunit, gamma isozyme L homeolog antikoerper, protein phosphatase 3, catalytic subunit, gamma isozyme, b antikoerper, PPP3CC antikoerper, Ppp3cc antikoerper, ppp3cca antikoerper, ppp3cc antikoerper, ppp3cc.L antikoerper, ppp3ccb antikoerper
Hintergrund
Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma, have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95 % amino acid identity).