NR3C2 Antikörper
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- Target Alle NR3C2 Antikörper anzeigen
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
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Reaktivität
- Human, Ratte, Kaninchen, Huhn
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser NR3C2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Marke
- IHC-plus™
- Spezifität
- Recognizes human MR (mineralocorticoid receptor). Detects a band of ~116kD by Western Blot. Species cross-reactivity: Rat, rabbit and chicken.
- Aufreinigung
- Protein G purified
- Immunogen
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Aldosterone.
Type of Immunogen: Hapten - Klon
- H10E4C9F
- Isotyp
- IgG1
- Top Product
- Discover our top product NR3C2 Primärantikörper
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- Applikationshinweise
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Approved: IHC, IHC-P (1:50), WB (1:250)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working dilution for LS-B3162 was determined to be 1:50. Function: Blocks the binding of aldosterone to the MR. - Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, pH 7.2, 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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LINC01128 resisted acute myeloid leukemia through regulating miR-4260/NR3C2." in: Cancer biology & therapy, Vol. 21, Issue 7, pp. 615-622, (2020) (PubMed).
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LINC01128 resisted acute myeloid leukemia through regulating miR-4260/NR3C2." in: Cancer biology & therapy, Vol. 21, Issue 7, pp. 615-622, (2020) (PubMed).
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- Target
- NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
- Andere Bezeichnung
- Mineralocorticoid Receptor (NR3C2 Produkte)
- Synonyme
- mr antikoerper, si:ch211-189l17.1 antikoerper, LOC100302443 antikoerper, NR3C2 antikoerper, LOC443144 antikoerper, MLR antikoerper, MR antikoerper, MCR antikoerper, NR3C2VIT antikoerper, Mlr antikoerper, mlr antikoerper, nuclear receptor subfamily 3, group C, member 2 antikoerper, nuclear receptor subfamily 3 group C member 2 antikoerper, mineralocorticoid receptor antikoerper, nuclear receptor subfamily 3 group C member 2 L homeolog antikoerper, nr3c2 antikoerper, NR3C2 antikoerper, LOC443144 antikoerper, Nr3c2 antikoerper, nr3c2.L antikoerper
- Hintergrund
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Name/Gene ID: NR3C2
Subfamily: NR3 Steroid receptor
Family: NHR
Synonyms: NR3C2, MCR, Mineralocorticoid receptor, NR3C2VIT, Aldosterone receptor, Mineralocorticoid receptor 1, MLR, MR - Gen-ID
- 4306
- UniProt
- P08235
- Pathways
- ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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