Swi6 (AA 314-328) Antikörper

Produktnummer ABIN401300

Produktdetails

Target: Swi6

Bindungsspezifität: AA 314-328

Reaktivität: Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to Swi6.

Aufreinigung: Affinity chromatography

Immunogen: Synthetic peptide corresponding aa 314-328 of S.pombe Swi6 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/5,000 - 1/30,000. Western Blot: 1/500 - 1/3,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.7 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Antigendetails

Target: Swi6

Hintergrund: Swi6 is also known as chromatinassociated swi6 protein and repression of silent mating type loci protein. This protein recognizes and binds to histone H3 tails that are methylated at Lys-9, leading to epigenetic repression. Swi6 is also involved in the repression of the silent mating-type loci MAT2 and MAT3 and it may be resposible for the compaction of MAT2/3 into a heterochromatin-like conformation which represses the transcription of these silent cassettes. Swi6 also interacts with the cohesin subunit psc3. Swi6 has a nuclear localization and contains 2 chromo domains.Synonyms: Chromatin-associated protein swi6

Gen-ID: 2541633

NCBI Accession: NP_593449

UniProt: P40381