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SYT1 Antikörper (pSer309)

SYT1 Reaktivität: Human, Ratte, Maus IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN401602
  • Target Alle SYT1 Antikörper anzeigen
    SYT1 (Synaptotagmin I (SYT1))
    Bindungsspezifität
    • 15
    • 12
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer309
    Reaktivität
    • 77
    • 67
    • 47
    • 11
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 87
    • 12
    • 6
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 96
    • 12
    Polyklonal
    Konjugat
    • 63
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SYT1 Antikörper ist unkonjugiert
    Applikation
    • 64
    • 39
    • 34
    • 16
    • 13
    • 13
    • 13
    • 10
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    Immunofluorescence (IF)
    Spezifität
    The antibody detects endogenous level of Synaptotagmin only when phosphorylated at Serine 309.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Mouse, Rat.
    Aufreinigung
    Affinity Chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
    Immunogen
    Peptide sequence around phosphorylation site of Serine 309 (G-L-S(p)-D-P) derived from Human.
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate Buffered Saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide, 50 % Glycerol
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    SYT1 (Synaptotagmin I (SYT1))
    Andere Bezeichnung
    Synaptotagmin-1 (SYT1 Produkte)
    Hintergrund
    The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse.Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65
    Molekulargewicht
    approx. 46 kDa
    Gen-ID
    6857
    NCBI Accession
    NP_001129277
    UniProt
    P21579
    Pathways
    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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