Paxillin Antikörper (Tyr88)
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- Target Alle Paxillin (PXN) Antikörper anzeigen
- Paxillin (PXN)
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Bindungsspezifität
- Tyr88
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Paxillin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Spezifität
- Paxillin Antibody detects endogenous levels of total Paxillin protein.
- Aufreinigung
- Affinity chromatography
- Immunogen
- Synthesized non-phosphopeptide derived from human Paxillin around the phosphorylation site of tyrosine 88 (P-V-YP-G-S).
- Top Product
- Discover our top product PXN Primärantikörper
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- Applikationshinweise
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Western Blot: 1/500 - 1/1000. Immunofluorescence: 1/100 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
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- Target
- Paxillin (PXN)
- Andere Bezeichnung
- Paxillin / PXN (PXN Produkte)
- Synonyme
- AW108311 antikoerper, AW123232 antikoerper, Pax antikoerper, CG18061 antikoerper, CG18576 antikoerper, CG31794 antikoerper, CT40481 antikoerper, CT42454 antikoerper, DPaxillin antikoerper, DPxn antikoerper, DPxn37 antikoerper, Dmel\\CG31794 antikoerper, Dpax antikoerper, DpaxA antikoerper, PDLP antikoerper, dPax antikoerper, pax antikoerper, wu:fw71f12 antikoerper, PXN antikoerper, LOC100220858 antikoerper, paxillin antikoerper, Paxillin antikoerper, paxillin S homeolog antikoerper, paxillin a antikoerper, PXN antikoerper, Pxn antikoerper, Pax antikoerper, pxn.S antikoerper, pxna antikoerper, LOC696336 antikoerper, pxn antikoerper
- Hintergrund
- Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).Synonyms: FLJ16691
- Gen-ID
- 5829
- NCBI Accession
- NP_001074324
- UniProt
- P49023
- Pathways
- MAPK Signalweg, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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