Unc5c Antikörper (Internal Region)

Produktnummer ABIN452309

Produktdetails anti-Unc5c Antikörper

Target: Unc5c (Unc-5 Homolog C (C. Elegans) (Unc5c))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Unc5c Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Sequenz: NCTVSEEPTG ID

Spezifität: This antibody recognizes UNC5C.

Kreuzreaktivität (Details): Species reactivity (expected):Human, Canine.
Species reactivity (tested):Mouse.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence NCTVSEEPTGID, from the internal region of the protein sequence . Genename: UNC5C

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu Unc5c

Target: Unc5c (Unc-5 Homolog C (C. Elegans) (Unc5c))

Andere Bezeichnung: UNC5C (Unc5c Produkte)

Hintergrund: UNC5C is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It is also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. There are two named isoforms.Synonyms: Netrin receptor UNC5C, Protein unc-5 homolog C, UNC5H3, Unc-5 homolog 3

Gen-ID: 8633

NCBI Accession: NP_003719

UniProt: O95185