Smooth Muscle Actin Antikörper (N-Term)
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- Target Alle Smooth Muscle Actin (ACTA2) Antikörper anzeigen
- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Ratte, Maus, Huhn, Rind (Kuh), Pferd
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Smooth Muscle Actin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- ASM-1 represents an excellent marker for myogenic soft tissue tumors and smooth muscle differentiation. Polypeptide reacting: specific for alpha-smooth-muscle isoform of actin (Mr 43,000). Tumors Specificallly Detected: leiomyosarcoma, leiomyoma, certain stromal cells surrounding infiltrating ductal carcinoma of breast. Tested Reactivities on Cultured Cell lines: Stress fibers of smooth muscle-derived cells and some smooth muscle subtype fibroblasts.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Bovine, Equine, Rat, Mouse and Chicken.
- Aufreinigung
- Affinity Chromatography on Protein A
- Immunogen
- Synthetic N- terminus decapeptide of alpha-smooth-muscleisoform of Actin.
- Klon
- ASM-1
- Isotyp
- IgG2a
- Top Product
- Discover our top product ACTA2 Primärantikörper
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- Applikationshinweise
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Immunofluorescence MicroscopyImmunoblotting (Western). Cytological Material. Immunohistochemistry on Frozen and Paraffin-Embedded Tissue. Pretreatment: With paraffin embedded sections, protease pretreatment is required prior toantibody application. Working Dilution: Ready-to-use for Immunohistochemical application. Incubation Time: 1 h at RT, extended with paraffin.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.09 % Sodium Azide, 0.5 % BSA
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody undiluited at 2-8 °CShelf life: One year from despatch.
- Haltbarkeit
- 12 months
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- Target
- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
- Abstract
- ACTA2 Produkte
- Synonyme
- AAT6 antikoerper, ACTSA antikoerper, MYMY5 antikoerper, GAMMA-ACTIN antikoerper, ACT antikoerper, ACTA3 antikoerper, ACTE antikoerper, ACTL3 antikoerper, ACTSG antikoerper, Act-4 antikoerper, Act4 antikoerper, SMGA antikoerper, 0610041G09Rik antikoerper, Actvs antikoerper, SMalphaA antikoerper, a-SMA antikoerper, alphaSMA antikoerper, wu:fb63d03 antikoerper, ASMA antikoerper, SMactin antikoerper, a-sma antikoerper, aat6 antikoerper, actsa antikoerper, mymy5 antikoerper, sm-actin antikoerper, ACTA2 antikoerper, actc1 antikoerper, ACT-4 antikoerper, asma antikoerper, ACTGE antikoerper, actin, alpha 2, smooth muscle, aorta antikoerper, actin, gamma 2, smooth muscle, enteric antikoerper, actin, alpha 2, smooth muscle, aorta L homeolog antikoerper, ACTA2 antikoerper, ACTG2 antikoerper, Actg2 antikoerper, Acta2 antikoerper, acta2 antikoerper, acta2.L antikoerper
- Hintergrund
- The two major cytoskeletal proteins implicated in cell motility are actin and myosin. Actin and myosin are constituents of many cell types and are involved in a myriad of cellular processes including locomotion, secretion, cytoplasmic streaming, phagocytosis and cytokinesis. Although actin is one of the most conserved eukaryotic proteins, it is expressed in mammals and birds as at least six isoforms characterized by electrophoresis and amino acid sequence analysis. Four of them represent the differentiation markers of muscle tissues and two are found in practically all cells.Synonyms: ACTSA, ACTVS, Alpha-actin-2, Cell growth-inhibiting gene 46 protein
- Gen-ID
- 58
- UniProt
- P68133
- Pathways
- Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
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