DISP1 Antikörper (C-Term)

Produktnummer ABIN452438

Produktdetails anti-DISP1 Antikörper

Target: DISP1 (Dispatched Homolog 1 (DISP1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser DISP1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Spezifität: This antibody reacts to Dispatched homolog 1.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography.

Immunogen: Peptide with sequence C-SELSGESLLIKTL, from the C Terminus of the protein sequence.

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Detection limit: 1/32000. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu DISP1

Target: DISP1 (Dispatched Homolog 1 (DISP1))

Andere Bezeichnung: DISP1 / DISPA (DISP1 Produkte)

Hintergrund: The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. Dispatched is a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells.Synonyms: Protein dispatched homolog 1

Gen-ID: 84976

NCBI Accession: NP_116279

UniProt: Q96F81

Pathways: Hedgehog Signalweg