CD41, CD61 Antikörper

Produktnummer ABIN452597

Produktdetails anti-CD41, CD61 Antikörper

Target: CD41, CD61 (CD41,CD61)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD41, CD61 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), Western Blotting (WB)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Produktmerkmale: Synonyms: Platelet Membrane GPIIb-IIIa Complex, CD41b, CD61, GP3A, GPIIIa, GPIIIb, GTA, HPA3,Integrin alpha 2b, Integrin beta 3

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: 10e9 Human platelets suspension. The supernatant fluid from positive clones was screened by ELISA coated with washedplatelets.

Klon: 237

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: This GPIIb/IIIa antibody is Suitable for use in ELISA and Western Blot. Use of this Monoclonal antibody at a concentration of 10-20 μg/mL (culture supernatants)will allow visualization of NP 40 solubilized human normal platelets. The titer of purified ascites was determined by ELISA coated with 100 μL of 1x10e8 washedplatelets.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.2 without preservatives.

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD41, CD61

Target: CD41, CD61 (CD41,CD61)

Abstract: CD41, CD61 Produkte

Hintergrund: The integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated alpha and beta subunits. CD61 non-covalently associates with CD41 (alpha Ilb integrin) and is expressed by megakaryocytes and platelets. The CD61/CD41 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb