GGCX Antikörper (C-Term)
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- Target Alle GGCX Antikörper anzeigen
- GGCX (gamma-Glutamyl Carboxylase (GGCX))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Hund
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser GGCX Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- GGCX antibody AP09596PU-N is expected to recognize both isoforms (NP_000812.2 and NP_001135741.1).
- Kreuzreaktivität (Details)
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Species reactivity (expected):Canine (Dog).
Species reactivity (tested):Human. - Aufreinigung
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
- Immunogen
- Peptide with sequence C-PPESNPDPVHSE, from the C-Terminus of the protein sequence according to NP_000812.2 and NP_001135741.1.
- Top Product
- Discover our top product GGCX Primärantikörper
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- Applikationshinweise
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Peptide ELISA: GGCX Antibody Detection limit dilution 1/32000. Western blot: 0.3-1 μg/mL. Approx 85 kDa band observed in Human Muscle lysates(calculated MW of 85 kDa according to NP_000812.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Target
- GGCX (gamma-Glutamyl Carboxylase (GGCX))
- Andere Bezeichnung
- GGCX (GGCX Produkte)
- Synonyme
- GGCX antikoerper, cb751 antikoerper, si:ch1073-230p18.3 antikoerper, zgc:158736 antikoerper, ggcx antikoerper, GGC antikoerper, vkcfd1 antikoerper, CG13927 antikoerper, DgammaC antikoerper, Dmel\\CG13927 antikoerper, dGC antikoerper, dgammaC antikoerper, gammaC antikoerper, VKCFD1 antikoerper, gamma-glutamyl carboxylase antikoerper, gamma-glutamyl carboxylase L homeolog antikoerper, GGCX antikoerper, ggcx antikoerper, GC antikoerper, sce5891 antikoerper, ggcx.L antikoerper, Ggcx antikoerper
- Hintergrund
- Gamma-glutamyl carboxylase GGCX is an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. GGCX accomplishes the posttranslational modification required for the activity of all of the vitamin K-dependent proteins (Wu et al., 1991 [PubMed 1749935]). These include some of the blood coagulation and anticoagulation proteins as well as bone gamma-carboxyglutamic acid (Gla) protein (BGLAP, MIM 112260) and bone matrix protein (MGP, MIM 154870).Synonyms: GC, Gamma-glutamyl carboxylase, Vitamin K gamma glutamyl carboxylase, Vitamin K-dependent gamma-carboxylase
- Gen-ID
- 2677
- NCBI Accession
- NP_000812
- UniProt
- P38435
- Pathways
- SARS-CoV-2 Protein Interaktom
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