LRRC32 Antikörper (AA 240-269)

Produktnummer ABIN453046

Produktdetails anti-LRRC32 Antikörper

Target: LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))

Bindungsspezifität: AA 240-269

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRC32 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects GARP at Center.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide between 240~269 amino acids from the Center region of Human GARP Genename: LRRC32

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000. Immunohistochemistry on paraffin sections: 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu LRRC32

Target: LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))

Andere Bezeichnung: LRRC32 / GARP (LRRC32 Produkte)

Hintergrund: GARP, also known as leucine rich repeat containing 32, is a type I membrane protein with twenty-two leucine-rich repeats and a short intracytoplasmic region. GARP was identified based on the analysis of gene expression profiling of Treg and Th cells following TCR stimulation. Since GARP is expressed in CD4+, CD25+, FoxP3+ cells (Tregs), it may be a candidate for cell surface marker for Treg cells.Synonyms: D11S833E, Garpin, Glycoprotein A repetitions predominant, Leucine-rich repeat-containing protein 32

Molekulargewicht: 71979 Da

Gen-ID: 2615

NCBI Accession: NP_001122394

UniProt: Q14392

Pathways: Activated T Cell Proliferation