FERMT3
Reaktivität: Human
Wirt: Kaninchen
Polyclonal
FITC
Applikationshinweise
Peptide ELISA: URP2 Antibody Detection limit dilution: 1/2000. Western blot: 1-3 μg/mL. Approx 75 kDa band observed in Human Peripheral BloodMononucleocytes lysates (calculated MW of 75.5 kDa according to NP_113659.3). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
C79673 antikoerper, Kindlin3 antikoerper, RGD1310168 antikoerper, MGC69069 antikoerper, MGC88900 antikoerper, KIND3 antikoerper, MIG-2 antikoerper, MIG2B antikoerper, UNC112C antikoerper, URP2 antikoerper, URP2SF antikoerper, zgc:64101 antikoerper, fermitin family member 3 antikoerper, fermitin family member 3 L homeolog antikoerper, fermitin family member 3b antikoerper, Fermt3 antikoerper, fermt3.L antikoerper, fermt3 antikoerper, FERMT3 antikoerper, fermt3b antikoerper
Hintergrund
URP2 is an essential element for platelet integrin activation in hemostasis and thrombosis. Platelets lacking the adhesion plaque protein URP2 cannot activate integrins despite normal Talin expression. As a direct consequence, URP2 deficiency results in severe bleeding and resistance to arterial thrombosis. URP2 binds directly bind to regions of beta-integrin tails and triggers integrin activation.Synonyms: Fermitin family homolog 3, KIND3, Kindlin-3, MIG2-like protein, MIG2B, URP2, Unc-112-related protein 2