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DPP4 Antikörper

DPP4 Reaktivität: Human FACS Wirt: Maus Monoclonal BA5b unconjugated
Produktnummer ABIN457416
  • Target Alle DPP4 Antikörper anzeigen
    DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
    Reaktivität
    • 130
    • 46
    • 41
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 82
    • 67
    • 19
    • 4
    • 1
    Maus
    Klonalität
    • 93
    • 77
    • 1
    Monoklonal
    Konjugat
    • 82
    • 25
    • 17
    • 14
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DPP4 Antikörper ist unkonjugiert
    Applikation
    • 78
    • 68
    • 42
    • 39
    • 35
    • 33
    • 25
    • 11
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody BA5b recognizes an extracellular epitope of CD26, a 110 kDa type II transmembrane glycoprotein, which is a peptidase expressed on mature thymocytes, T cells (especially activated), B cells, NK cells and macrophages.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    A human T cell clone
    Klon
    BA5b
    Isotyp
    IgG2a
    Top Product
    Discover our top product DPP4 Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-2 μg/mL, positive control: human peripheral blood leukocytes.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
    Andere Bezeichnung
    CD26 (DPP4 Produkte)
    Hintergrund
    Dipeptidyl peptidase 4,CD26, also known as dipeptidyl peptidase IV (DPP-IV), is a homodimeric cell surface serine peptidase that degradates IFN-gamma-induced cytokines, acts as a T cell costimulatory molecule, and participates in multiple immunopathological roles in leukocyte homing and inflammation. Alterations in its peptidase activity are characteristic of malignant transformation. The enzymatic activity increases dramatically with tumour grade and severity. CD26 is expressed in various blood cell types, but also e.g. in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.,DPP4, TP103, ADCP-2, ADABP
    Gen-ID
    1803
    UniProt
    P27487
    Pathways
    Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
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