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ENPP3 Antikörper

Name: ENPP3 Antikörper
Brand: antibodies-online
SKU: ABIN457434
Price: 334.72 EUR
Availability: InStock

ENPP3 Reaktivität: Human FACS, ICC Wirt: Maus Monoclonal NP4D6 unconjugated

Flow cytometry surface staining pattern of IgE stimulated human peripheral whole blood stained using anti-human CD203c (NP4D6) purified antibody (concentration in sample 2 μg/mL, GAM APC). (ENPP3 Antikörper)

FACS

Separation of CD203c positive basophil granulocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of IgE stimulated human peripheral whole blood using anti-human CD203c (NP4D6) purified antibody (concentration in sample 2 μg/mL, GAM APC). (ENPP3 Antikörper)

FACS

2 Abbildungen

(2 Referenzen)

Produktnummer ABIN457434

Datenblatt (PDF)

Target Alle ENPP3 Antikörper anzeigen

ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))
Reaktivität
72

34

18

4

4

3

2

1

1
Human
Wirt
52

20
Maus
Passende Sekundärantikörper
Klonalität
53

19
Monoklonal
Konjugat
22

8

6

6

4

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser ENPP3 Antikörper ist unkonjugiert
Applikation
33

26

25

13

13

9

6

4

3

3

2

1

1

1
Flow Cytometry (FACS), Immunocytochemistry (ICC)

Spezifität

The mouse monoclonal antibody NP4D6 reacts with an extracellular epitope of CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.

Kreuzreaktivität (Details)

Human

Aufreinigung

Purified by protein-A affinity chromatography.

Reinheit

> 95 % (by SDS-PAGE)

Immunogen

HEK-293 cells transfected with human CD203c

Klon

NP4D6

Isotyp

IgG1

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anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (Internal Region) antibody
ENPP3 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (AA 45-163) antibody
ENPP3 Reaktivität: Human ELISA, FACS, IHC Wirt: Maus Monoclonal 4C1H2 unconjugated

anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (Internal Region) antibody
ENPP3 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibody (PE)
ENPP3 Reaktivität: Human FACS, ICC Wirt: Maus Monoclonal NP4D6 PE

anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibody (APC)
ENPP3 Reaktivität: Human FACS Wirt: Maus Monoclonal NP4D6 APC

anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (Internal Region) antibody
ENPP3 Reaktivität: Human, Hund, Affe IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibody (FITC)
ENPP3 Reaktivität: Human FACS Wirt: Maus Monoclonal NP4D6 FITC

anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (AA 40-140) antibody
ENPP3 Reaktivität: Human, Ratte ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (AA 814-843), (C-Term) antibody
ENPP3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB24586 unconjugated

anti-Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) (AA 602-699) antibody
ENPP3 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1G11 unconjugated

Applikationshinweise

Flow cytometry: Recommended dilution: 1-4 μg/mL. Extracellular and intracellular staining.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1 mg/mL

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Do not freeze.

Lagerung

4 °C

Informationen zur Lagerung

Store at 2-8°C. Do not freeze.
Heneberg, Riegerová, Kučera: "Pimecrolimus Is a Potent Inhibitor of Allergic Reactions to Hymenopteran Venom Extracts and Birch Pollen Allergen In Vitro." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142953, (2015) (PubMed).

Platz, Binder, Marxer, Lischka, Valent, Bühring: "Hymenoptera-venom-induced upregulation of the basophil activation marker ecto-nucleotide pyrophosphatase/phosphodiesterase 3 in sensitized individuals." in: International archives of allergy and immunology, Vol. 126, Issue 4, pp. 335-42, (2002) (PubMed).
Target

ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))

Andere Bezeichnung

CD203c (ENPP3 Produkte)

Synonyme

B10 antikoerper, CD203c antikoerper, NPP3 antikoerper, PD-IBETA antikoerper, PDNP3 antikoerper, Npp3 antikoerper, RB13-6 antikoerper, AI876438 antikoerper, ENPP3 antikoerper, ectonucleotide pyrophosphatase/phosphodiesterase 3 antikoerper, ectonucleotide pyrophosphatase/phosphodiesterase 3 L homeolog antikoerper, ENPP3 antikoerper, Enpp3 antikoerper, enpp3 antikoerper, enpp3.L antikoerper

Hintergrund

Ectonucleotide pyrophosphatase/phosphodiesterase 3,CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.,ENPP3, B10, PDNP3, PD-IBETA

Gen-ID

5169

UniProt

O14638

Pathways

Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity