beta-Thromboglobulin Antikörper

Produktnummer ABIN458153

Produktdetails anti-beta-Thromboglobulin Antikörper

Target: beta-Thromboglobulin (beta-TG)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser beta-Thromboglobulin Antikörper ist unkonjugiert

Applikation: ELISA, Immunodiffusion (ID), Nephelometry (Neph)

Spezifität: Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. of this antiserum has not been tested in detail.

Produktmerkmale: Precipitating polyclonal rabbit antiserum to human beta-thromboglobulin

Aufreinigung: Adsorption: Immunoaffinity adsorbed using insolubilized antigens as required, to eliminate antibodies reacting with other human serum proteins. The use of insolubilized adsorption antigens prevents the presence of excess adsorbent protein or immune complexes in the antiserum.

Immunogen: Beta-thromboglobulin is a platelet specific protein. In normal plasma mean concentrations of 30 ng/ml have been found. Highly purified beta-thromboglobulin has been isolated from platelets and is used for the immunization. Freund’s complete adjuvant is used in the first step of the immunization procedure.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: In plasma the beta-thromboglobulin can only be assayed in more sensitive methods as ELISA, because of the low concentration of the antigen: in electroimmunodiffusion (Laurell), immunonephelometry, solid phase assays and as catching or detection antibody in ELISA. Measurements of beta-thromboglobulin is of significance for the diagnosis of platelet disorders involving platelet alpha granules and to demonstrate increased platelet secretions in vivo.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Total protein and IgG concentrations in the antiserum are comparable to those of normal pooled rabbit serum. No foreign proteins added. Antibody titre: The amount of beta-thromboglobulin precipitated by 1 ml antiserum is approximately 0.2 mg.

Buffer: Delipidated, heat inactivated, lyophilized, stable whole serum.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: The lyophilized antiserum is shipped at ambient temperature and may be stored at +4°C, prolonged storage at or below -20°C. Reconstitute the lyophilized antiserum by adding 1 ml sterile distilled water. Dilutions may be prepared by adding phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the antiserum. Diluted antiserum should be stored at +4°C, not ref rozen, and preferably used the same day.

Details zu beta-Thromboglobulin

Target: beta-Thromboglobulin (beta-TG)

Andere Bezeichnung: beta-Thromboglobulin (beta-TG Produkte)

Synonyme: B-TG1 antikoerper, Beta-TG antikoerper, CTAP-III antikoerper, CTAP3 antikoerper, CTAPIII antikoerper, CXCL7 antikoerper, LA-PF4 antikoerper, LDGF antikoerper, MDGF antikoerper, NAP-2 antikoerper, PBP antikoerper, SCYB7 antikoerper, TC1 antikoerper, TC2 antikoerper, TGB antikoerper, TGB1 antikoerper, THBGB antikoerper, THBGB1 antikoerper, CTAPIII/NAP-2 antikoerper, 2400003M24Rik antikoerper, AI854500 antikoerper, Cxcl7 antikoerper, NAP-2-L1 antikoerper, Scyb7 antikoerper, b-TG1 antikoerper, beta-TG antikoerper, Nap-2 antikoerper, pro-platelet basic protein antikoerper, PPBP antikoerper, Ppbp antikoerper

Hintergrund: The defined antibody specificity is restricted to beta-thromboglobulin as tested at the level of sensitivity of immunoprecipitation techniques. A single precipitin line is obtained in bid-dimensional electrophoresis against normal plasma and platelet concentrate lysate, which shows a reaction of identity with precipitated purified beta-thromboglobulin. The antiserum does not react with any other protein component of human serum or plasma