C6 Antikörper (C-Term)

Produktnummer ABIN461987

Produktdetails anti-C6 Antikörper

Target: C6 (Complement Component 6 (C6))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser C6 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Recognizes complement component 6 (C6) a 104 kD member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C terminus of the C5b alpha-chain, anchoring the molecule to the membrane and also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. Recognizes MAC.

Aufreinigung: Protein A purified

Immunogen: Purified human C6.

Klon: 056B-214-2-4-2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, Flo, IHC, IHC-P (10 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL. Histology Positive Control Tissue: Kidney from post streptococcal glomerulonephritis patients.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Borate buffered saline, 0.09 % sodium azide. Sourced in Ascites.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. Store undiluted.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.

Details zu C6

Target: C6 (Complement Component 6 (C6))

Andere Bezeichnung: Complement C6 (C6 Produkte)

Synonyme: zgc:64073 antikoerper, MGC82168 antikoerper, c6 antikoerper, MGC89471 antikoerper, C6 antikoerper, AW111623 antikoerper, complement component 6 antikoerper, complement C6 antikoerper, complement component 6, gene 1 L homeolog antikoerper, complement component 6, gene 2 antikoerper, c6 antikoerper, C6 antikoerper, c6.1.L antikoerper, c6.2 antikoerper

Hintergrund: Name/Gene ID: C6

Synonyms: C6, Complement component C6, Complement C6, Complement component 6

Gen-ID: 729

UniProt: P13671