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C6 Antikörper (C-Term)

C6 Reaktivität: Human IHC, ELISA, FACS, IHC (p) Wirt: Maus Monoclonal 056B-214-2-4-2 unconjugated
Produktnummer ABIN461987
  • Target Alle C6 Antikörper anzeigen
    C6 (Complement Component 6 (C6))
    Bindungsspezifität
    • 14
    • 8
    • 3
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 36
    • 5
    • 3
    Human
    Wirt
    • 31
    • 6
    • 2
    Maus
    Klonalität
    • 33
    • 5
    Monoklonal
    Konjugat
    • 21
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    Dieser C6 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 25
    • 23
    • 21
    • 8
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Marke
    IHC-plus™
    Spezifität
    Recognizes complement component 6 (C6) a 104 kD member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C terminus of the C5b alpha-chain, anchoring the molecule to the membrane and also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. Recognizes MAC.
    Aufreinigung
    Protein A purified
    Immunogen
    Purified human C6.
    Klon
    056B-214-2-4-2
    Isotyp
    IgG1
    Top Product
    Discover our top product C6 Primärantikörper
  • Applikationshinweise
    Approved: ELISA, Flo, IHC, IHC-P (10 μg/mL)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL. Histology Positive Control Tissue: Kidney from post streptococcal glomerulonephritis patients.
    Kommentare

    Target Species of Antibody: Human

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Borate buffered saline, 0.09 % sodium azide. Sourced in Ascites.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing. Store undiluted.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
  • Target
    C6 (Complement Component 6 (C6))
    Andere Bezeichnung
    Complement C6 (C6 Produkte)
    Synonyme
    zgc:64073 antikoerper, MGC82168 antikoerper, c6 antikoerper, MGC89471 antikoerper, C6 antikoerper, AW111623 antikoerper, complement component 6 antikoerper, complement C6 antikoerper, complement component 6, gene 1 L homeolog antikoerper, complement component 6, gene 2 antikoerper, c6 antikoerper, C6 antikoerper, c6.1.L antikoerper, c6.2 antikoerper
    Hintergrund
    Name/Gene ID: C6

    Synonyms: C6, Complement component C6, Complement C6, Complement component 6
    Gen-ID
    729
    UniProt
    P13671
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