SPTLC1 Antikörper

Produktnummer ABIN4620353

Produktdetails anti-SPTLC1 Antikörper

Target: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPTLC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody detects Serine Palmitoyltransferase 1, ubiquitously expressed.

Aufreinigung: Antigen Immunoaffinity Chromatography

Immunogen: Synthetic peptide derived from the Human Sserine Palmitoyltransferase enzyme

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: (1-5 μg/mL). Immunohistochemistry: (1-5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SPTLC1

Target: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Andere Bezeichnung: SPTLC1 (SPTLC1 Produkte)

Hintergrund: Sphingolipids play essential roles in various cellular events, including proliferation, differentiation, senescence, apoptosis, and inflammatory responses. Serine palmitoyltransferase (SPT) is the initial and rate-limiting enzyme in the de novo sphingolipid biosynthesis, and thus regulates the level of sphingolipids in cells. Immunohistochemical study revealed widespread distribution of the enzyme with most strong expression in brain and digestive tract. Two subunits, SPT1 and SPT2 at a stoichiometry of 1:1, are involved in the enzymatic activity of SPT.Synonyms: LCB 1, LCB1, Long chain base biosynthesis protein 1, SPT 1, SPT1, Serine palmitoyltransferase 1, Serine-palmitoyl-CoA transferase 1

Molekulargewicht: 52.7 kDa

Gen-ID: 10558

NCBI Accession: NP_006406

UniProt: O15269