Calprotectin Antikörper (Biotin)

Produktnummer ABIN481652

Produktdetails anti-Calprotectin Antikörper (Biotin)

Target: Calprotectin (S100A8/A9)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Calprotectin Antikörper ist konjugiert mit Biotin

Applikation: Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: The antigen is MRP8/14 (calprotectin), the epitope involves parts of both subunits MRP8 and MRP14. Antigen distribution: Isolated cells: Monocytes carry the antigen both on the surface and intracellularly, granulocytes exhibit it only intracellularly. Up to 80 % of monocytes in early cultures (24- 48h) are positive. No reaction has been seen with lymphocytes or platelets. Tissue sections: The antigen is found in macrophages in the red pulp of the spleen and liver. It is strongly expressed in macrophages from acute inflamed tissues (peridontitis, contact eczema, urticaria, erythrodermia) where some endothelial and epidermal cells may also express this antigen. It is normally absent on resident mononuclear phagocytes in healthy tissues (skin, gut, thymus). Specificity: Human: subpopulation of macrophages, monocytes and granulocytes, peripheral blood monocytes carry the antigen extra- and intracellularly, neutrophils only intracellularly. Other: subpopulation of macrophages of rhesus monkey and bovine tissues. The antibody does not react with swine tissues.

Aufreinigung: Affinity purified

Immunogen: Cultured human monocytes

Klon: 27E10

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, IHC, IHC-P

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 0.5 mL distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS  pH 7.2, 5 mg/mL BSA, and 0.05 % Kathon CG

Konservierungsmittel: Kathon CG

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C.

Details zu Calprotectin

Target: Calprotectin (S100A8/A9)

Andere Bezeichnung: Calprotectin (S100A8/A9 Produkte)

Pathways: S100 Proteine