MORF4L1 Antikörper (N-Term)

Produktnummer ABIN487997

Produktdetails anti-MORF4L1 Antikörper

Target: MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser MORF4L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: APKQDPKPKF QEG-C

Spezifität: This antibody recognizes MRG15 and is expected to recognise Isoform 1 (NP_006782.1) and Isoform 2 (NP_996670.1).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Porcine, Bovine.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography

Immunogen: Syntehtic peptide from the N-Terminus of Human MORF4L1 (NP_006782.1, NP_996670.1) . Genename: MORF4L1

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/64000. Western blot: Preliminary experiments gave an approx 40 kDa band in Human Liver lysatesand an approx 100 kDa band in Human Heart lysates at 1 μg/mL. Please note that currentlywe cannot find an explanation in the literature for the bands we observe given thecalculated size of 37.0 kDda according to NP_006782.1. Immunohistochemistry on paraffin sections: Human Uterus shows nuclear staining in theepithelial cells of the endometrial glands. Recommended concentration: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu MORF4L1

Target: MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))

Andere Bezeichnung: MRG15 (MORF4L1 Produkte)

Hintergrund: MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.Synonyms: FWP006, HSPC008, HSPC061, MORF-related gene 15 protein, MORF4L1, MRG15, MSL3-1 protein, Mortality factor 4-like protein 1, PP368, Transcription factor-like protein MRG15

Molekulargewicht: 37.2 kDa (Mouse NP_077751.1).

Gen-ID: 10933

NCBI Accession: NP_006782

UniProt: Q9UBU8

Pathways: Chromatin Binding