ADO Antikörper (AA 49-261)
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- Target Alle ADO Antikörper anzeigen
- ADO (2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO))
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Bindungsspezifität
- AA 49-261
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ADO Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Verwendungszweck
- Rabbit IgG polyclonal antibody for 2-aminoethanethiol dioxygenase(ADO) detection. Tested with WB in Human,Mouse,Rat.
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for 2-aminoethanethiol dioxygenase(ADO) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: 2-aminoethanethiol dioxygenase
Protein Name: 2-aminoethanethiol dioxygenase - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- E. coli-derived human ADO recombinant protein (Position: E49-E261). Human ADO shares 90.1% amino acid (aa) sequence identity with mouse ADO.
- Isotyp
- IgG
- Top Product
- Discover our top product ADO Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- ADO (2-Aminoethanethiol (Cysteamine) Dioxygenase (ADO))
- Andere Bezeichnung
- ADO (ADO Produkte)
- Synonyme
- C10orf22 antikoerper, Gm237 antikoerper, RGD1308233 antikoerper, wu:fc32g01 antikoerper, wu:fc52c12 antikoerper, zgc:101580 antikoerper, 2-aminoethanethiol dioxygenase antikoerper, 2-aminoethanethiol (cysteamine) dioxygenase antikoerper, 2-aminoethanethiol (cysteamine) dioxygenase a antikoerper, ADO antikoerper, Ado antikoerper, LOC100351598 antikoerper, adoa antikoerper
- Hintergrund
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Human thiol dioxygenases include cysteine dioxygenase (CDO) and cysteamine (2-aminoethanethiol) dioxygenase (ADO). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine. It is demonstrated that mouse Ado has strong and specific dioxygenase activity in vitro towards cysteamine but not cysteine. Recombinant Ado was shown to bind iron. Overexpression of Ado in HepG2/C3A cells increased the production of hypotaurine from cysteamine. Similar results were found with human ADO. When endogenous expression of ADO was reduced by RNA-mediated interference, hypotaurine production decreased. It is also noted that the demonstration of high levels of ADO in brain challenges the previous assumption that most of the taurine in the brain is a consequence of CDO activity.
Synonyms: ADO | C10orf22 | Cysteamine dioxygenase | Q96SZ5 - Gen-ID
- 84890
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