AKR1B1 Antikörper (AA 228-316)
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- Target Alle AKR1B1 Antikörper anzeigen
- AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))
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Bindungsspezifität
- AA 228-316
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser AKR1B1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Aldose reductase(AKR1B1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for Aldose reductase(AKR1B1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: aldo-keto reductase family 1 member B
Protein Name: Aldose reductase - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- E. coli-derived human AKR1B1 recombinant protein (Position: L228-F316). Human AKR1B1 shares 87.5% amino acid (aa) sequence identity with both mouse and rat AKR1B1.
- Isotyp
- IgG
- Top Product
- Discover our top product AKR1B1 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))
- Andere Bezeichnung
- AKR1B1 (AKR1B1 Produkte)
- Synonyme
- ADR antikoerper, ALDR1 antikoerper, ALR2 antikoerper, AR antikoerper, ALDRED antikoerper, ALR-P-I antikoerper, Akr1b3 antikoerper, Akr1b4 antikoerper, Aldr1 antikoerper, Alr antikoerper, RATALDRED antikoerper, akr1b7 antikoerper, zgc:86611 antikoerper, aldo-keto reductase family 1 member B antikoerper, aldo-keto reductase family 1, member B1 (aldose reductase) antikoerper, aldo-keto reductase family 1, member B1 (aldose reductase) S homeolog antikoerper, AKR1B1 antikoerper, Akr1b1 antikoerper, akr1b1.S antikoerper, akr1b1 antikoerper
- Hintergrund
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Aldo-keto reductase family 1, member B1 (aldose reductase), also known as AR, is an enzyme that in humans is encoded by the AKR1B1 gene. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number ofaldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol.
Synonyms: ADR | AKR1B 1 | Akr1b1 | Aldehyde reductase 1 | Aldehyde reductase | Aldose reductase | aldr 1 | aldr1 | ALR2 | AR | P15121 - Gen-ID
- 231
- UniProt
- P15121
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process
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