AMFR Antikörper (AA 553-643)

Produktnummer ABIN4886455

Produktdetails anti-AMFR Antikörper

Target: AMFR (Autocrine Motility Factor Receptor (AMFR))

Bindungsspezifität: AA 553-643

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AMFR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase AMFR(AMFR) detection. Tested with WB, IHC-P in Human,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase AMFR(AMFR) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: autocrine motility factor receptor
Protein Name: E3 ubiquitin-protein ligase AMFR

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human AMFR recombinant protein (Position: E553-S643). Human AMFR shares 89% amino acid (aa) sequence identity with mouse AMFR.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu AMFR

Target: AMFR (Autocrine Motility Factor Receptor (AMFR))

Andere Bezeichnung: AMFR (AMFR Produkte)

Synonyme: GP78 antikoerper, RNF45 antikoerper, gp78 antikoerper, wu:fi06e06 antikoerper, wu:fi37e05 antikoerper, zgc:63893 antikoerper, rnf45 antikoerper, autocrine motility factor receptor antikoerper, autocrine motility factor receptor L homeolog antikoerper, autocrine motility factor receptor a antikoerper, autocrine motility factor receptor, amfr antikoerper, putative autocrine motility factor receptor, amfr antikoerper, AMFR antikoerper, Amfr antikoerper, amfr.L antikoerper, amfra antikoerper, amfr antikoerper, AaeL_AAEL005881 antikoerper, CpipJ_CPIJ016043 antikoerper, Smp_047420 antikoerper

Hintergrund: Autocrine motility factor receptor, isoform 2 is a protein that in humans is encoded by the AMFR gene. Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. The protein encoded by this gene is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins.

Synonyms: AMF receptor | AMFR | gp78 | RNF 45 | RNF45 | Q9UKV5

Gen-ID: 267

Pathways: ER-Nucleus Signaling