APOA1 Antikörper (AA 25-267)
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- Target Alle APOA1 Antikörper anzeigen
- APOA1 (Apolipoprotein A-I (APOA1))
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Bindungsspezifität
- AA 25-267
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser APOA1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Apolipoprotein A-I(APOA1) detection. Tested with WB, IHC-P, ELISA in Human.
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for Apolipoprotein A-I(APOA1) detection. Tested with WB, IHC-P, ELISA in Human.
Gene Name: apolipoprotein A-I
Protein Name: Apolipoprotein A-I - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- E. coli-derived human APOA1 recombinant protein (Position: D25-Q267). Human APOA1 shares 64% and 61.7% amino acid (aa) sequence identity with mouse and rat APOA1, respectively.
- Isotyp
- IgG
- Top Product
- Discover our top product APOA1 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- APOA1 (Apolipoprotein A-I (APOA1))
- Andere Bezeichnung
- APOA1 (APOA1 Produkte)
- Synonyme
- Alp-1 antikoerper, Apoa-1 antikoerper, Brp-14 antikoerper, Ltw-1 antikoerper, Lvtw-1 antikoerper, Sep-1 antikoerper, Sep-2 antikoerper, Sep2 antikoerper, apoA-I antikoerper, apoa antikoerper, apoa1 antikoerper, cb49 antikoerper, wu:fb33f01 antikoerper, zgc:103718 antikoerper, MGC64335 antikoerper, MGC89745 antikoerper, Apo-AI antikoerper, ApoA-I antikoerper, APOA1 antikoerper, LOC100136573 antikoerper, apoa-i antikoerper, ApoAI antikoerper, apolipoprotein A1 antikoerper, apolipoprotein A-I antikoerper, apolipoprotein A-Ia antikoerper, apolipoprotein A-I S homeolog antikoerper, apolipoprotein A4 antikoerper, APOA1 antikoerper, Apoa1 antikoerper, apoa1a antikoerper, apoa1.S antikoerper, apoa1 antikoerper, LOC100136573 antikoerper, apoa-i antikoerper, apoa4 antikoerper
- Hintergrund
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Apolipoprotein A-1, also known as APOA1, is a human protein with a specific role in lipid metabolism. It binds to lipopolysaccharide or endotoxin, and has a major role in the anti-endotoxin function of HDL. The gene is mapped to 11q23. And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence. The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. ApoA-I is also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect. Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Additionally, ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport.
Synonyms: Apo AI | APOA 1 | ApoA I | APOA1 | ApoA-I | Apo-AI | Apolipoprotein A I | Apolipoprotein A1 | Apolipoprotein AI | Apolipoprotein A-I | Apolipoprotein A-I(1-242) | ProapoA-I | Proapolipoprotein A-I | Truncated apolipoprotein A-I | P02647 - Gen-ID
- 335
- UniProt
- P02647
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
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