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CD58 Antikörper (AA 29-215)

CD58 Reaktivität: Human FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN4886530
  • Target Alle CD58 Antikörper anzeigen
    CD58
    Bindungsspezifität
    • 15
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-215
    Reaktivität
    • 81
    • 5
    • 2
    • 1
    • 1
    Human
    Wirt
    • 42
    • 39
    Kaninchen
    Klonalität
    • 42
    • 39
    Polyklonal
    Konjugat
    • 30
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD58 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 36
    • 13
    • 13
    • 11
    • 9
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Lymphocyte function-associated antigen 3(CD58) detection. Tested with WB, IHC-P, FCM in Human.
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Lymphocyte function-associated antigen 3(CD58) detection. Tested with WB, IHC-P, FCM in Human.
    Gene Name: CD58 Molecule
    Protein Name: Lymphocyte function-associated antigen 3
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E. coli-derived human LFA3 recombinant protein (Position: F29-R215).
    Isotyp
    IgG
    Top Product
    Discover our top product CD58 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Flow Cytometry: Concentration:1-3 μg/1x106 cells, Tested Species: Human
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    CD58
    Andere Bezeichnung
    CD58 (CD58 Produkte)
    Synonyme
    LFA-3 antikoerper, LFA3 antikoerper, ag3 antikoerper, CD58 molecule antikoerper, CD58 antikoerper
    Hintergrund
    CD58, or lymphocyte function-associated antigen 3 (LFA-3), is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. It binds to CD2 (LFA-2) on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. This adhesion occurs as part of the transitory initial encounters between T cells and Antigen Presenting Cells before T cell activation, when T cells are roaming the lymph nodes looking at the surface of APCs for peptide:MHC complexes the T-cell receptors are reactive to. The LFA3 gene is mapped to chromosome 1p13, which is the same location as CD2.

    Synonyms: AG3 | CD58 | CD58 antigen | CD58 Molecule | LFA 3 | LFA-3 | LFA3 | P19256
    Gen-ID
    965
    UniProt
    P19256
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