Diazepam Binding Inhibitor Antikörper (AA 2-87)

Produktnummer ABIN4886558

Produktdetails anti-Diazepam Binding Inhibitor Antikörper

Target: Diazepam Binding Inhibitor (DBI)

Bindungsspezifität: AA 2-87

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Diazepam Binding Inhibitor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Acyl-CoA-binding protein(DBI) detection. Tested with WB, IHC-P in Human.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Acyl-CoA-binding protein(DBI) detection. Tested with WB, IHC-P in Human.
Gene Name: diazepam binding inhibitor, acyl-CoA binding protein
Protein Name: Acyl-CoA-binding protein

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human DBI recombinant protein (Position: S2-I87). Human DBI shares 77.9% amino acid (aa) sequence identity with both mouse and rat DBI.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu Diazepam Binding Inhibitor

Target: Diazepam Binding Inhibitor (DBI)

Andere Bezeichnung: DBI (DBI Produkte)

Synonyme: ACBD1 antikoerper, ACBP antikoerper, CCK-RP antikoerper, EP antikoerper, dbib antikoerper, DBI antikoerper, wu:fb63e10 antikoerper, zgc:56108 antikoerper, zgc:77734 antikoerper, Acbp antikoerper, endozepine antikoerper, Acoabp3 antikoerper, Ep antikoerper, Odn antikoerper, RNACOABP3 antikoerper, Ttn antikoerper, acbd1 antikoerper, acbp antikoerper, cck-rp antikoerper, dbi antikoerper, dbi-a antikoerper, dbi-b antikoerper, dbia antikoerper, diazepam binding inhibitor, acyl-CoA binding protein antikoerper, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) S homeolog antikoerper, diazepam-binding inhibitor antikoerper, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) antikoerper, acyl-CoA-binding protein antikoerper, diazepam binding inhibitor antikoerper, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) L homeolog antikoerper, DBI antikoerper, dbi.S antikoerper, dbi antikoerper, LOC706367 antikoerper, Dbi antikoerper, dbi.L antikoerper

Hintergrund: Acyl-CoA-binding protein is a protein that in humans is encoded by the DBI gene. This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

Synonyms: ACBD 1 | ACBD1 | ACBP | CCK RP | CCKRP | DBI | Endozepine | EP | P07108

Gen-ID: 1622

UniProt: P07108