LDHB Antikörper (AA 237-334)

Produktnummer ABIN4886658

Produktdetails anti-LDHB Antikörper

Target: LDHB (Lactate Dehydrogenase B (LDHB))

Bindungsspezifität: AA 237-334

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LDHB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for L-lactate dehydrogenase B chain(LDHB) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for L-lactate dehydrogenase B chain(LDHB) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: lactate dehydrogenase B
Protein Name: L-lactate dehydrogenase B chain

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human LDHB recombinant protein (Position: E237-L334). Human LDHB shares 98% amino acid (aa) sequence identity with both mouse and rat LDHB.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu LDHB

Target: LDHB (Lactate Dehydrogenase B (LDHB))

Andere Bezeichnung: LDHB (LDHB Produkte)

Synonyme: LDH-B antikoerper, LDH-H antikoerper, LDHBD antikoerper, TRG-5 antikoerper, AI790582 antikoerper, H-Ldh antikoerper, Ldh-2 antikoerper, Ldh2 antikoerper, ldh-h antikoerper, ldh2 antikoerper, ldhb antikoerper, ldhba antikoerper, trg-5 antikoerper, LDHB antikoerper, LDH-B-A antikoerper, wu:fa16d07 antikoerper, wu:fa20c10 antikoerper, wu:fa96a08 antikoerper, LDH-B-B antikoerper, zgc:92882 antikoerper, lactate dehydrogenase B antikoerper, lactate dehydrogenase B S homeolog antikoerper, lactate dehydrogenase Ba antikoerper, lactate dehydrogenase Bb antikoerper, LDHB antikoerper, Ldhb antikoerper, ldhb.S antikoerper, ldhb antikoerper, ldhba antikoerper, ldhbb antikoerper

Hintergrund: The LDHB gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

Synonyms: HEL S 281 | LDHB | LDH-B | LDH B | LDHH | LDH-H | LDH H | LDHBD | TRG-5 | TRG5 | P07195

Gen-ID: 3945

UniProt: P07195

Pathways: Warburg Effekt