SAFB Antikörper (C-Term)
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- Target Alle SAFB Antikörper anzeigen
- SAFB (Scaffold Attachment Factor B (SAFB))
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Bindungsspezifität
- AA 715-754, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SAFB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Scaffold attachment factor B1(SAFB) detection. Tested with WB in Human.
- Sequenz
- DLDRRDDAYW PEAKRAALDE RYHSDFNRQD RFHDFDHRDR
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for Scaffold attachment factor B1(SAFB) detection. Tested with WB in Human.
Gene Name: scaffold attachment factor B
Protein Name: Scaffold attachment factor B1 - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human SAFB (715-754aa DLDRRDDAYWPEAKRAALDERYHSDFNRQDRFHDFDHRDR), different from the related mouse and rat sequences by five amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product SAFB Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- SAFB (Scaffold Attachment Factor B (SAFB))
- Andere Bezeichnung
- SAFB (SAFB Produkte)
- Synonyme
- HAP antikoerper, HET antikoerper, SAF-B1 antikoerper, SAFB1 antikoerper, 3110021E02Rik antikoerper, 5330423C17Rik antikoerper, AU018122 antikoerper, D18386 antikoerper, E130307D12 antikoerper, zgc:55387 antikoerper, wu:fb40a03 antikoerper, wu:fd42g06 antikoerper, SAFB2 antikoerper, SAFB antikoerper, scaffold attachment factor B antikoerper, scaffold attachment factor B S homeolog antikoerper, SAFB-like transcription modulator antikoerper, Scaffold attachment factor B antikoerper, SAFB antikoerper, Safb antikoerper, safb antikoerper, safb.S antikoerper, LOC5570070 antikoerper, CpipJ_CPIJ017179 antikoerper, Bm1_49330 antikoerper, LOAG_00080 antikoerper
- Hintergrund
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Scaffold attachment factor B, also known as SAFB, is a gene with homologs that have been studied in humans and mice. This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: HAP | HET | SAF B | SAF-B | SAF-B1 | SAFB 1 | SAFB | SAFB1 | Q15424 - Gen-ID
- 6294
- UniProt
- Q15424
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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