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TLN2 Antikörper (Middle Region)

TLN2 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN4886745
  • Target Alle TLN2 Antikörper anzeigen
    TLN2 (Talin 2 (TLN2))
    Bindungsspezifität
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 1787-1822, Middle Region
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 17
    • 2
    • 1
    Kaninchen
    Klonalität
    • 17
    • 3
    Polyklonal
    Konjugat
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TLN2 Antikörper ist unkonjugiert
    Applikation
    • 10
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Talin-2(TLN2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Sequenz
    NPKAQHTHDA ITEAAQLMKE AVDDIMVTLN EAASEV
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Talin-2(TLN2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: talin 2
    Protein Name: Talin-2
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence in the middle region of human Talin 2 (1787-1822aa NPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEV).
    Isotyp
    IgG
    Top Product
    Discover our top product TLN2 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Li, Li, Qi, Rychahou, Jafari, Huang: "The role of talin2 in breast cancer tumorigenesis and metastasis." in: Oncotarget, Vol. 8, Issue 63, pp. 106876-106887, (2017) (PubMed).

  • Target
    TLN2 (Talin 2 (TLN2))
    Andere Bezeichnung
    TLN2 (TLN2 Produkte)
    Synonyme
    TLN2 antikoerper, ilweq antikoerper, talin-2 antikoerper, ILWEQ antikoerper, 5730421P04Rik antikoerper, AI507121 antikoerper, AI787438 antikoerper, AL118320 antikoerper, mKIAA0320 antikoerper, RGD1565416 antikoerper, talin 2 antikoerper, talin 2 S homeolog antikoerper, TLN2 antikoerper, tln2.S antikoerper, tln2 antikoerper, Tln2 antikoerper
    Hintergrund
    Talin 2 is a protein in humans that is encoded by the TLN2 gene. It belongs to the talin protein family. This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. Talin-2 is expressed at high levels in cardiac muscle and functions to provide linkages between the extracellular matrix and actin cytoskeleton at costamere structures to transduce force laterally.

    Synonyms: Talin2 | Talin 2 | Talin-2 | TLN2 | TLN 2 | TLN-2 | ILWEQ | Q9Y4G6
    Gen-ID
    83660
    UniProt
    Q9Y4G6
    Pathways
    Cell-Cell Junction Organization, Maintenance of Protein Location
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