8-OHDG Antikörper

Produktnummer ABIN488679

Produktdetails anti-8-OHDG Antikörper

Target: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Reaktivität: Bitte anfragen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser 8-OHDG Antikörper ist unkonjugiert

Applikation: ELISA, Affinity Purification (AP), Immunostaining (ISt)

Spezifität: Recognizes markers of oxidative damage to DNA (8-hydroxy-2?-deoxyguanosine,8-hydroxyguanine and 8-hydroxyguanosine).

Aufreinigung: affinity purified

Immunogen: 8-hydroxy-guanosine-BSA and - casein conjugates

Klon: 15A3

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Recommended Dilution needs to be determined for each application.

Kommentare:

protocol for immunostaining using this antibody can be found here

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: protein G purified IgG2B in PBS, pH 7.4 with 0.09 % sodium azide and 50 %glycerol at concentration 0.65 mg/mL

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.
Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

Lagerung: -20 °C

Referenzen für anti-8-OHDG Antikörper (ABIN488679)

Haigh, Drew: "Cavitation during the protein misfolding cyclic amplification (PMCA) method--The trigger for de novo prion generation?" in: Biochemical and biophysical research communications, Vol. 461, Issue 3, pp. 494-500, (2015) (PubMed).

Bobal, Otevrel, Poborilova, Vaverkova, Csollei, Babula: "Application of BY-2 cell model in evaluating an effect of newly prepared potential calcium channel blockers." in: Pakistan journal of pharmaceutical sciences, Vol. 28, Issue 4, pp. 1281-93, (2015) (PubMed).

Pilger, Rüdiger: "8-Hydroxy-2'-deoxyguanosine as a marker of oxidative DNA damage related to occupational and environmental exposures." in: International archives of occupational and environmental health, Vol. 80, Issue 1, pp. 1-15, (2006) (PubMed).

Details zu 8-OHDG

Target: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Andere Bezeichnung: 8-Hydroxyguanosine (8-OHDG Produkte)

Substanzklasse: Chemical

Hintergrund: Oxidative derivate of guanosine is called 8-Hydroxyguanosine (8OHdG) and is used as a popular biomarker of oxidative stress.