p53 Antikörper
-
- Target Alle p53 (TP53) Antikörper anzeigen
- p53 (TP53) (Tumor Protein P53 (TP53))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser p53 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Spezifität
- Reacts with human truncated p53 from MCF7 cells and endogenous p53 from various tumour cells
- Aufreinigung
- Purified (protein A)
- Immunogen
- Recombinant 6-histidine-troncated p53(6H-Cp53)
- Klon
- H53C2
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product TP53 Primärantikörper
-
anti-Tumor Protein P53 (TP53) (N-Term) antibody
TP53 Reaktivität: Human WB, IF, IHC (p), IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) antibodyKO Validated TP53 Reaktivität: Human WB, IF, IHC (p), IP, ICC, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (pSer392) antibodyTP53 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (AA 1-100) antibodyTP53 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (AA 301-393) antibodyTP53 Reaktivität: Human, Maus, Ratte, Ziege WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (AA 293-322) antibodyTP53 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB7777 unconjugated
anti-Tumor Protein P53 (TP53) (pSer33) antibodyTP53 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tumor Protein P53 (TP53) (AA 94-201) antibodyTP53 Reaktivität: Human WB, ELISA, IF, IHC (p), IP Wirt: Maus Monoclonal 2C3 unconjugated
anti-Tumor Protein P53 (TP53) (AA 94-201) antibodyTP53 Reaktivität: Human WB, ELISA, IHC (p), PLA, RNAi Wirt: Maus Monoclonal 2C11 unconjugated
anti-Tumor Protein P53 (TP53) (acLys319) antibodyTP53 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
-
Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC(1:100 - 1:500) IP (1:50 - 1:200) WB(1:200 - 1:1000) - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Must be reconstituted in distilled water.
- Konzentration
- 1 mg/mL
- Buffer
- Tris 0,1M, glycine 0,1M, sucrose 2 %
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Haltbarkeit
- 24 months
-
- Target
- p53 (TP53) (Tumor Protein P53 (TP53))
- Andere Bezeichnung
- Cellular Tumor Antigen p53 (TP53 Produkte)
- Hintergrund
- Belongs to the p53 family. Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis, the function is largely independent of transcription.
- Gen-ID
- 7157
- UniProt
- P04637
- Pathways
- p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie, Warburg Effekt
-
