NBR1 Antikörper

Produktnummer ABIN4901991

Produktdetails anti-NBR1 Antikörper

Target: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NBR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: NBR1 is a protein encoded by the NBR1 gene which is approximately 107,4 kDa. NBR1 is localised to the cytoplasm and is involved in animal mitophagy. It contains a B-box/coiled-coil motif and functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. NBR1 is expressed in the nervous system, bone marrow, lung and muscle. Mutations in the NBR1 gene may result in inclusion body myositis and synucleinopathy. STJ98902 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody detects endogenous NBR1 protein.

Spezifität: The antibody detects endogenous NBR1 protein.

Produktmerkmale: Mouse Monoclonal to NBR1.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Recombinant peptide derived from NBR1.

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000
ELISA 1:10000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu NBR1

Target: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Andere Bezeichnung: NBR1 (NBR1 Produkte)

Synonyme: fa99f08 antikoerper, wu:fa99f08 antikoerper, MGC69008 antikoerper, NBR1 antikoerper, 1A1-3B antikoerper, M17S2 antikoerper, mKIAA0049 antikoerper, Ca125 antikoerper, RGD1311421 antikoerper, neighbor of brca1 gene 1a antikoerper, neighbor of BRCA1 gene 1 L homeolog antikoerper, NBR1, autophagy cargo receptor antikoerper, neighbor of Brca1 gene 1 antikoerper, nbr1a antikoerper, nbr1.L antikoerper, NBR1 antikoerper, Nbr1 antikoerper

Molekulargewicht: 120kDa

Gen-ID: 4077

UniProt: Q14596

Pathways: Autophagie