Hemoglobin Subunit beta Antikörper

Produktnummer ABIN4903870

Produktdetails anti-Hemoglobin Subunit beta Antikörper

Target: Hemoglobin Subunit beta (HBB) (Hemoglobin beta (HBB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Hemoglobin Subunit beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktmerkmale: Hemoglobin (Hgb) is coupled to four iron-binding, methene-linked tetrapyrrole rings (heme). The å (16p13.3, 5'-Ω-pseudoz-pseudo å2-pseudo å1-å2-å1-1-3') and (11p15.5) globin loci determine the basic hemoglobin structure. The globin portion of hemoglobin consists of two å chains and two chains arranged in pairs forming a tetramer. Each of the four globin chains covalently associates with a heme group. The bonds between å and chains are weaker than between similar globin chains, thereby forming a cleavage plane that is important for oxygen binding and release. High affinity for oxygen occurs upon relaxation of the å1-2 cleavage plane. When the two å1-2 interfaces are closely bound, hemoglobin has a low affinity for oxygen. Hb A, which contains two å chains plus two chains, comprises 97 % of total circulating hemoglobin. The remaining 3 % of total circulating hemoglobin is comprised of Hb A-2, which consists of two å chains plus two chains, and fetal hemoglobin (Hb F), which consists of two å chains together with two © chains.

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human HBB.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:100-1:200 , IHC 1:50-1:100 , FC 1:20-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.

Details zu Hemoglobin Subunit beta

Target: Hemoglobin Subunit beta (HBB) (Hemoglobin beta (HBB))

Andere Bezeichnung: HBB (HBB Produkte)

Synonyme: HBB antikoerper, HBB1 antikoerper, HBBA antikoerper, HBBB antikoerper, CD113t-C antikoerper, beta-globin antikoerper, hbb antikoerper, hemoglobin, beta antikoerper, hemoglobin subunit beta antikoerper, hemoglobin subunit beta-like antikoerper, beta globin antikoerper, hemoglobin beta chain complex antikoerper, hemoglobin subunit beta-1 antikoerper, HBB antikoerper, HBB2 antikoerper, LOC100720944 antikoerper, LOC480784 antikoerper, Hbb antikoerper, LOC100136576 antikoerper, LOC101098159 antikoerper, LOC100976465 antikoerper, LOC100410611 antikoerper, LOC105468624 antikoerper

Substanzklasse: Viral Protein

Gen-ID: 3043

UniProt: P68871