IL12RB2 Antikörper

Produktnummer ABIN4904030

Produktdetails anti-IL12RB2 Antikörper

Target: IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL12RB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene.

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human IL12RB2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.

Details zu IL12RB2

Target: IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

Andere Bezeichnung: IL12RB2 (IL12RB2 Produkte)

Synonyme: IL12RB2 antikoerper, A930027I18Rik antikoerper, IL-12RB2 antikoerper, Ifnm antikoerper, interleukin 12 receptor subunit beta 2 antikoerper, interleukin 12 receptor, beta 2 antikoerper, IL12RB2 antikoerper, Il12rb2 antikoerper

Gen-ID: 3595

UniProt: Q99665

Pathways: JAK-STAT Signalweg