ATG4A Antikörper

Produktnummer ABIN4906361

Produktdetails anti-ATG4A Antikörper

Target: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ATG4A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein G.

Immunogen: This ATG4A antibody is generated from a mouse immunized with a recombinant protein.

Klon: 14C9

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IF()

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu ATG4A

Target: ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

Andere Bezeichnung: ATG4A (ATG4A Produkte)

Synonyme: apg4a antikoerper, autl2 antikoerper, F6E13.27 antikoerper, APG4A antikoerper, zgc:111958 antikoerper, Aut2a antikoerper, AUTL2 antikoerper, AI627006 antikoerper, AV169859 antikoerper, Apg4a antikoerper, Atg4al antikoerper, Autl2 antikoerper, Atg4a antikoerper, autophagy related 4A cysteine peptidase L homeolog antikoerper, autophagy related 4A cysteine peptidase antikoerper, Peptidase family C54 protein antikoerper, ATG4 autophagy related 4 homolog A (S. cerevisiae) antikoerper, autophagy related 4A, cysteine peptidase antikoerper, atg4a.L antikoerper, ATG4A antikoerper, AT2G44140 antikoerper, atg4a antikoerper, Atg4a antikoerper

Hintergrund:

Synonyms: APG4A, AUTL2, Cysteine protease ATG4A, AUT-like 2 cysteine endopeptidase, Autophagin-2, Autophagy-related cysteine endopeptidase 2, Autophagy-related protein 4 homolog A, hAPG4A, ATG4A

Background: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Gen-ID: 115201

UniProt: Q8WYN0

Pathways: Autophagie