ATG4A Antikörper
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- Target Alle ATG4A Antikörper anzeigen
- ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ATG4A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunofluorescence (Cultured Cells) (IF (cc))
- Kreuzreaktivität
- Human
- Aufreinigung
- Purified by Protein G.
- Immunogen
- This ATG4A antibody is generated from a mouse immunized with a recombinant protein.
- Klon
- 14C9
- Isotyp
- IgG2b
- Top Product
- Discover our top product ATG4A Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IF() - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
- Andere Bezeichnung
- ATG4A (ATG4A Produkte)
- Hintergrund
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Synonyms: APG4A, AUTL2, Cysteine protease ATG4A, AUT-like 2 cysteine endopeptidase, Autophagin-2, Autophagy-related cysteine endopeptidase 2, Autophagy-related protein 4 homolog A, hAPG4A, ATG4A
Background: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.
- Gen-ID
- 115201
- UniProt
- Q8WYN0
- Pathways
- Autophagie
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