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RCAN3 Antikörper (AA 151-241) (AbBy Fluor® 594)

RCAN3 Reaktivität: Maus, Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 594
Produktnummer ABIN2811039
  • Target Alle RCAN3 Antikörper anzeigen
    RCAN3 (RCAN Family Member 3 (RCAN3))
    Bindungsspezifität
    • 15
    • 14
    • 9
    • 7
    • 6
    • 2
    • 1
    AA 151-241
    Reaktivität
    • 40
    • 30
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 53
    • 1
    Kaninchen
    Klonalität
    • 53
    • 1
    Polyklonal
    Konjugat
    • 14
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RCAN3 Antikörper ist konjugiert mit AbBy Fluor® 594
    Applikation
    • 40
    • 29
    • 21
    • 12
    • 12
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Calcipressin 3
    Isotyp
    IgG
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  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    RCAN3 (RCAN Family Member 3 (RCAN3))
    Andere Bezeichnung
    Calcipressin 3 (RCAN3 Produkte)
    Synonyme
    DSCR1L2 antikoerper, rcn3 antikoerper, hrcn3 antikoerper, mcip3 antikoerper, dscr1l2 antikoerper, MGC145788 antikoerper, MCIP3 antikoerper, RCN3 antikoerper, hRCN3 antikoerper, Dscr1l2 antikoerper, AU041093 antikoerper, Csp3 antikoerper, wu:fc68f05 antikoerper, zgc:113155 antikoerper, zgc:91820 antikoerper, RCAN family member 3 antikoerper, calcipressin-3 antikoerper, regulator of calcineurin 3 antikoerper, RCAN3 antikoerper, Tsp_08182 antikoerper, rcan3 antikoerper, Rcan3 antikoerper
    Hintergrund

    Synonyms: Calcipressin-3, Down syndrome candidate region 1 like 2, regulator of calcineurin 3, Down syndrome candidate region 1 like protein 2, Down syndrome candidate region 1-like protein 2, Down syndrome critical region gene 1 like 2, DSCR1L2, hRCN3, MCIP3, Myocyte enriched calcineurin interacting protein 3, Myocyte-enriched calcineurin-interacting protein 3, RCAN family member 3, RCAN3, RCAN3_HUMAN, RCN3, Regulator of calcineurin 3.

    Background: Calcineurin is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions. Proteins belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFATs (Nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. Calcipressin-2, also known as RCAN2 and DSCR1L1 (Down syndrome candidate region 1-like 1), is a 197 amino acid protein that is highly expressed in both the cytoplasm and nucleus of neurons and is the only RCAN family member that is found in glial cells. Calcipressin-3, also known as RCAN3 and DSCR1L2 (Down syndrome candidate region 1-like protein 2), is a 241 amino acid protein that potentially is involved in central nervous system development. Calcipressin-3 interacts with cardiac troponin I, suggesting that it may play a role in cardiac contraction events.

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