COPS3 Antikörper (AA 261-360)
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- Target Alle COPS3 Antikörper anzeigen
- COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))
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Bindungsspezifität
- AA 261-360
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser COPS3 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human COPS3
- Isotyp
- IgG
- Top Product
- Discover our top product COPS3 Primärantikörper
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anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 324-422) antibody
COPS3 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 2D10 unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 324-422) antibodyCOPS3 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 194-423) antibodyCOPS3 Reaktivität: Human WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 324-422) antibodyCOPS3 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2D10 unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (C-Term) antibodyCOPS3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 139-390) antibodyCOPS3 Reaktivität: Human, Ratte WB, IHC, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) antibodyCOPS3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 98-130) antibodyCOPS3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB17614 unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) antibodyCOPS3 Reaktivität: Human, Maus, Ratte WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 3 (COPS3) (AA 194-423) antibodyCOPS3 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))
- Andere Bezeichnung
- COPS3 (COPS3 Produkte)
- Hintergrund
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Synonyms: COP9 signalosome complex subunit 3, SGN3, Signalosome subunit 3, JAB1-containing signalosome subunit 3
Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
- Gen-ID
- 8533
- Pathways
- Zellzyklus
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