Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

DDR1 Antikörper

DDR1 Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal 4C4 unconjugated
Produktnummer ABIN4908648
  • Target Alle DDR1 Antikörper anzeigen
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    Reaktivität
    • 82
    • 34
    • 34
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 86
    • 11
    Maus
    Klonalität
    • 85
    • 11
    • 1
    Monoklonal
    Konjugat
    • 47
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser DDR1 Antikörper ist unkonjugiert
    Applikation
    • 74
    • 37
    • 26
    • 26
    • 19
    • 12
    • 12
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by Protein G.
    Immunogen
    This DDR1 antibody is generated from a mouse immunized with a recombinant protein.
    Klon
    4C4
    Isotyp
    IgG2b
    Top Product
    Discover our top product DDR1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    Andere Bezeichnung
    DDR1 (DDR1 Produkte)
    Hintergrund

    Synonyms: CAK, DDR, NEP, HGK2, PTK3, RTK6, TRKE, CD167, EDDR1, MCK10, NTRK4, PTK3A, Epithelial discoidin domain-containing receptor 1, Epithelial discoidin domain receptor 1, CD167 antigen-like family member A, Cell adhesion kinase, Discoidin receptor tyrosine kinase, Mammary carcinoma kinase 10, MCK-10, Protein-tyrosine kinase 3A, Protein-tyrosine kinase RTK-6, TRK E, Tyrosine kinase DDR, Tyrosine-protein kinase CAK, CD167a, DDR1

    Background: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.

    Gen-ID
    780
    UniProt
    Q08345
    Pathways
    RTK Signalweg, Smooth Muscle Cell Migration
Sie sind hier:
Kundenservice