DDR2 Antikörper
-
- Target Alle DDR2 Antikörper anzeigen
- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser DDR2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Human
- Aufreinigung
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
- Immunogen
- This DDR2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 290-320 amino acids from human DDR2.
- Klon
- 3E5
- Isotyp
- IgG1
- Top Product
- Discover our top product DDR2 Primärantikörper
-
-
- Applikationshinweise
- WB 1:300-5000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
- Andere Bezeichnung
- DDR2 (DDR2 Produkte)
- Synonyme
- MIG20a antikoerper, NTRKR3 antikoerper, TKT antikoerper, TYRO10 antikoerper, AW495251 antikoerper, Ntrkr3 antikoerper, tyro10 antikoerper, DDR2 antikoerper, Tyro10 antikoerper, ddr2 antikoerper, si:ch211-193c2.1 antikoerper, discoidin domain receptor tyrosine kinase 2 antikoerper, discoidin domain receptor family, member 2 antikoerper, discoidin domain receptor family, member 2, like antikoerper, DDR2 antikoerper, Ddr2 antikoerper, ddr2l antikoerper
- Hintergrund
-
Synonyms: TKT, MIG20a, NTRKR3, TYRO10, Discoidin domain-containing receptor 2, Discoidin domain receptor 2, CD167 antigen-like family member B, Discoidin domain-containing receptor tyrosine kinase 2, Neurotrophic tyrosine kinase, receptor-related 3, Receptor protein-tyrosine kinase TKT, Tyrosine-protein kinase TYRO10, CD167b, DDR2
Background: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.
- Gen-ID
- 4921
- UniProt
- Q16832
- Pathways
- RTK Signalweg
-