HINT1 Antikörper

Produktnummer ABIN4910644

Produktdetails anti-HINT1 Antikörper

Target: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HINT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein G.

Immunogen: This HINT1 antibody is generated from a mouse immunized with a recombinant protein of human HINT1.

Klon: 5C3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IF()

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu HINT1

Target: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Andere Bezeichnung: HINT1 (HINT1 Produkte)

Synonyme: hint antikoerper, pkci-1 antikoerper, prkcnh1 antikoerper, HINT antikoerper, NMAN antikoerper, PKCI-1 antikoerper, PRKCNH1 antikoerper, AA673479 antikoerper, Hint antikoerper, Ipk1 antikoerper, Pkci antikoerper, Prkci antikoerper, zgc:103764 antikoerper, CHPKCI antikoerper, HINTZ antikoerper, PKCIZ antikoerper, histidine triad nucleotide binding protein 1 antikoerper, histidine triad nucleotide binding protein 1 S homeolog antikoerper, histidine triad nucleotide binding protein 1-Z antikoerper, Histidine triad nucleotide-binding protein 1 antikoerper, HINT1 antikoerper, hint1 antikoerper, Hint1 antikoerper, hint1.S antikoerper, HINT1Z antikoerper, hint-1 antikoerper

Hintergrund:

Synonyms: HINT, NMAN, PKCI-1, PRKCNH1, Histidine triad nucleotide-binding protein 1, Adenosine 5'-monophosphoramidase, Protein kinase C inhibitor 1, Protein kinase C-interacting protein 1, HINT1, PKCI1

Background: Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.

Gen-ID: 3094

UniProt: P49773