Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

MASTL Antikörper

MASTL Reaktivität: Human WB Wirt: Maus Monoclonal 5C3 unconjugated
Produktnummer ABIN4911795
  • Target Alle MASTL Antikörper anzeigen
    MASTL (Microtubule Associated serine/threonine Kinase-Like (MASTL))
    Reaktivität
    • 45
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 46
    • 13
    Maus
    Klonalität
    • 45
    • 14
    Monoklonal
    Konjugat
    • 25
    • 7
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MASTL Antikörper ist unkonjugiert
    Applikation
    • 45
    • 38
    • 8
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Human
    Aufreinigung
    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
    Immunogen
    This MASTL monoclonal antibody is generated from mouse immunized with MASTL recombinant protein.
    Klon
    5C3
    Isotyp
    IgG1
    Top Product
    Discover our top product MASTL Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    MASTL (Microtubule Associated serine/threonine Kinase-Like (MASTL))
    Andere Bezeichnung
    MASTL (MASTL Produkte)
    Synonyme
    GW antikoerper, GWL antikoerper, MAST-L antikoerper, im:7149025 antikoerper, wu:fa02a12 antikoerper, zgc:100990 antikoerper, MASTL antikoerper, GREATWALL antikoerper, RP11-85G18.2 antikoerper, THC2 antikoerper, hGWL antikoerper, 2700091H24Rik antikoerper, C88295 antikoerper, greatwall antikoerper, thc2 antikoerper, microtubule associated serine/threonine kinase-like antikoerper, microtubule associated serine/threonine kinase like antikoerper, serine/threonine-protein kinase greatwall antikoerper, microtubule associated serine/threonine kinase like L homeolog antikoerper, mastl antikoerper, MASTL antikoerper, LOC100541707 antikoerper, Mastl antikoerper, mastl.L antikoerper
    Hintergrund

    Synonyms: GW, GWL, THC2, MAST-L, GREATWALL, Serine/threonine-protein kinase greatwall, hGWL, Microtubule-associated serine/threonine-protein kinase-like, MASTL

    Background: Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited. Phosphorylates histone protein in vitro, however such activity is unsure in vivo. May be involved in megakaryocyte differentiation.

    Gen-ID
    84930
    UniProt
    Q96GX5
Sie sind hier:
Kundenservice