MBD3 Antikörper
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- Target Alle MBD3 Antikörper anzeigen
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MBD3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Human
- Aufreinigung
- Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogen
- Purified His-tagged MBD3 protein was used to produced this monoclonal antibody.
- Klon
- 5C3
- Isotyp
- IgG1
- Top Product
- Discover our top product MBD3 Primärantikörper
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- Applikationshinweise
- WB 1:300-5000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
- Andere Bezeichnung
- MBD3 (MBD3 Produkte)
- Synonyme
- xmbd3 antikoerper, MGC69548 antikoerper, MBD3 antikoerper, DKFZp459N1635 antikoerper, AI181826 antikoerper, AU019209 antikoerper, methyl-CpG binding domain protein 3 S homeolog antikoerper, methyl-CpG binding domain protein 3 antikoerper, mbd3.S antikoerper, mbd3 antikoerper, MBD3 antikoerper, Mbd3 antikoerper
- Hintergrund
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Synonyms: Methyl-CpG-binding domain protein 3, Methyl-CpG-binding protein MBD3, MBD3
Background: Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases.
- Gen-ID
- 53615
- UniProt
- O95983
- Pathways
- Chromatin Binding
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