MGMT Antikörper
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- Target Alle MGMT Antikörper anzeigen
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MGMT Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human
- Aufreinigung
- Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogen
- Purified His-tagged MGMT protein was used to produced this monoclonal antibody.
- Klon
- 4C12
- Isotyp
- IgG1
- Top Product
- Discover our top product MGMT Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IF() - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
- Andere Bezeichnung
- MGMT (MGMT Produkte)
- Synonyme
- AGT antikoerper, AI267024 antikoerper, Agat antikoerper, O-6-methylguanine-DNA methyltransferase antikoerper, MGMT antikoerper, Mgmt antikoerper
- Hintergrund
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Synonyms: Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase
Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
- Gen-ID
- 4255
- UniProt
- P16455
- Pathways
- DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus
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