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MGMT Antikörper

MGMT Reaktivität: Human WB, IF, IHC (p) Wirt: Maus Monoclonal 4C12 unconjugated
Produktnummer ABIN4911931
  • Target Alle MGMT Antikörper anzeigen
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    Reaktivität
    • 72
    • 19
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 69
    • 10
    Maus
    Klonalität
    • 62
    • 17
    Monoklonal
    Konjugat
    • 44
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser MGMT Antikörper ist unkonjugiert
    Applikation
    • 54
    • 33
    • 20
    • 20
    • 13
    • 13
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    Purified His-tagged MGMT protein was used to produced this monoclonal antibody.
    Klon
    4C12
    Isotyp
    IgG1
    Top Product
    Discover our top product MGMT Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IF()
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    Andere Bezeichnung
    MGMT (MGMT Produkte)
    Synonyme
    AGT antikoerper, AI267024 antikoerper, Agat antikoerper, O-6-methylguanine-DNA methyltransferase antikoerper, MGMT antikoerper, Mgmt antikoerper
    Hintergrund

    Synonyms: Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase

    Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

    Gen-ID
    4255
    UniProt
    P16455
    Pathways
    DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus
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